Microglia-Derived Extracellular Vesicles Carrying miR-711 Alleviate Neurodegeneration in a Murine Alzheimer’s Disease Model by Binding to Itpkb

Microglia-Derived Extracellular Vesicles Carrying miR-711 Alleviate Neurodegeneration in a Murine Alzheimer’s Disease Model by Binding to Itpkb

Neurodegeneration in Alzheimer’s disease (AD) results in microglial activation, which may participate in the inflammatory cascade accelerating tissue damage. In this study, we sought to characterize the alleviatory role of microRNA-711 (miR-711) encapsulated in microglia-derived extracellular vesicl...

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Bibliographic Details
Main Authors: Yizhi Zhang, Chengbi Xu, Yi Nan, Shanji Nan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
extracellular vesicles
microRNA-711
Alzheimer’s disease
Itpkb
Tau
microglia
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.566530/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.566530/full

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