Restriction endonucleases from invasive Neisseria gonorrhoeae cause double-strand breaks and distort mitosis in epithelial cells during infection.

Restriction endonucleases from invasive Neisseria gonorrhoeae cause double-strand breaks and distort mitosis in epithelial cells during infection.

The host epithelium is both a barrier against, and the target for microbial infections. Maintaining regulated cell growth ensures an intact protective layer towards microbial-induced cellular damage. Neisseria gonorrhoeae infections disrupt host cell cycle regulation machinery and the infection caus...

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Bibliographic Details
Main Authors: Linda Weyler, Mattias Engelbrecht, Manuel Mata Forsberg, Karl Brehwens, Daniel Vare, Katarina Vielfort, Andrzej Wojcik, Helena Aro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4252111?pdf=render

Internet

http://europepmc.org/articles/PMC4252111?pdf=render

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