Downregulation of the protein synthesis machinery is a major regulatory event during early adipogenic differentiation of human adipose-derived stromal cells

Downregulation of the protein synthesis machinery is a major regulatory event during early adipogenic differentiation of human adipose-derived stromal cells

Commitment of adult stem cells involves the activation of specific gene networks regulated from transcription to protein synthesis. Here, we used ribosome profiling to identify mRNAs regulated at the translational level, through both differential association to polysomes and modulation of their tran...

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Bibliographic Details
Main Authors: Bruna H. Marcon, Fabíola B. Holetz, Guillermo Eastman, Ana Carolina Origa-Alves, Mariana Andrea Amorós, Alessandra Melo de Aguiar, Carmen K. Rebelatto, Paulo R.S. Brofman, Jose Sotelo-Silveira, Bruno Dallagiovanna
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Stem Cell Research
Subjects:
hASCs
Adipogenesis
Ribosome profiling
Translation
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117302301

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http://www.sciencedirect.com/science/article/pii/S1873506117302301

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