Acid sphingomyelinase deficiency protects mitochondria and improves function recovery after brain injury

Traumatic brain injury (TBI) is one of the leading causes of disability worldwide and a prominent risk factor for neurodegenerative diseases. The expansion of nervous tissue damage after the initial trauma involves a multifactorial cascade of events, including excitotoxicity, oxidative stress, infla...

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Bibliographic Details
Main Authors: Sergei A. Novgorodov, Joshua R. Voltin, Wenxue Wang, Stephen Tomlinson, Christopher L. Riley, Tatyana I. Gudz
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520326225