Genome-wide association study to identify the genetic determinants of otitis media susceptibility in childhood.

BACKGROUND: Otitis media (OM) is a common childhood disease characterised by middle ear inflammation and effusion. Susceptibility to recurrent acute OM (rAOM; ≥ 3 episodes of AOM in 6 months) and chronic OM with effusion (COME; MEE ≥ 3 months) is 40-70% heritable. Few underlying genes have been iden...

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Bibliographic Details
Main Authors: Marie S Rye, Nicole M Warrington, Elizabeth S H Scaman, Shyan Vijayasekaran, Harvey L Coates, Denise Anderson, Craig E Pennell, Jenefer M Blackwell, Sarra E Jamieson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485007?pdf=render