Synergistic Effect of Dietary Betaines on SIRT1-Mediated Apoptosis in Human Oral Squamous Cell Carcinoma Cal 27

Synergistic Effect of Dietary Betaines on SIRT1-Mediated Apoptosis in Human Oral Squamous Cell Carcinoma Cal 27

Betaines are food components widely distributed in plants, animals, microorganisms, and dietary sources. Among betaines, δ-valerobetaine (<i>N,N,N</i>-trimethyl-5-aminovaleric acid, δVB) shares a metabolic pathway common to γ-butyrobetaine (γBB). The biological properties of δVB are part...

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Bibliographic Details
Main Authors: Nunzia D’Onofrio, Luigi Mele, Elisa Martino, Angela Salzano, Brunella Restucci, Domenico Cautela, Marco Tatullo, Maria Luisa Balestrieri, Giuseppe Campanile
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
δ-valerobetaine
betaine
oxidative stress
apoptosis
SIRT1
oral carcinoma
Online Access:https://www.mdpi.com/2072-6694/12/9/2468

Internet

https://www.mdpi.com/2072-6694/12/9/2468

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