Increase of Neutrophil Activation Markers in Venous Thrombosis—Contribution of Circulating Activated Protein C

Upon activation, neutrophils release their content through different mechanisms like degranulation and NETosis, thus prompting thrombosis. The natural anticoagulant activated protein C (APC) inhibits neutrophil NETosis and, consequently, this may lower the levels of neutrophil activation markers in...

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Bibliographic Details
Main Authors: Laura Martos, Julia Oto, Álvaro Fernández-Pardo, Emma Plana, María José Solmoirago, Fernando Cana, David Hervás, Santiago Bonanad, Fernando Ferrando, Francisco España, Silvia Navarro, Pilar Medina
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
DNA
Online Access:https://www.mdpi.com/1422-0067/21/16/5651