Designing a new tetrapeptide to inhibit the BIR3 domain of the XIAP protein via molecular dynamics simulations
The XIAP protein is a member of apoptosis proteins family. The XIAP protein plays a central role in the inhibition of apoptosis and consists of three Baculoviral IAP Repeat domains. The BIR3 domain binds directly to the N-terminal of caspase-9 and therefore it inhibits apoptosis. N-terminal tetrapep...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Kharazmi University
2018-09-01
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| Series: | یافتههای نوین در علوم زیستی |
| Subjects: | |
| Online Access: | http://nbr.khu.ac.ir/browse.php?a_code=A-10-81-124&slc_lang=en&sid=1 |