Baicalin Ameliorates Pancreatic Fibrosis by Inhibiting the Activation of Pancreatic Stellate Cells in Mice with Chronic Pancreatitis

Baicalin Ameliorates Pancreatic Fibrosis by Inhibiting the Activation of Pancreatic Stellate Cells in Mice with Chronic Pancreatitis

Pancreatic inflammation and fibrosis are typical pathological features in chronic pancreatitis (CP). Activated pancreatic stellate cells (PSCs) have been regarded as the core event in the development of pancreatic fibrosis and are considered to be the key target for treatment of CP. Baicalin (C21H18...

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Bibliographic Details
Main Authors: Jianwei Fan, Lifang Duan, Nan Wu, Xiaofan Xu, Jiaqi Xin, Shengnan Jiang, Cheng Zhang, Hong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
baicalin
pancreatic inflammation
pancreatic fibrosis
pancreatic stellate cells
nuclear factor-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.607133/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.607133/full

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