Clinical Efficacy, Safety, and Immunogenicity of a Live Attenuated Tetravalent Dengue Vaccine (CYD-TDV) in Children: A Systematic Review with Meta-analysis

Clinical Efficacy, Safety, and Immunogenicity of a Live Attenuated Tetravalent Dengue Vaccine (CYD-TDV) in Children: A Systematic Review with Meta-analysis

BackgroundDengue hemorrhagic fever is the leading cause of hospitalization and death in children living in Asia and Latin America. There is an urgent need for an effective and safe dengue vaccine to reduce morbidity and mortality in this high-risk population given the lack of dengue specific treatme...

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Bibliographic Details
Main Authors: Moffat Malisheni, Svetlana F. Khaiboullina, Albert A. Rizvanov, Noah Takah, Grant Murewanhema, Matthew Bates
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
dengue hemorrhagic fever
dengue shock syndrome
CYD-TDV
dengue virus
efficacy
safety
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00863/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00863/full

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