Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity

Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity

Serology is an important way to monitor SARS-CoV-2 infection in the population and support vaccine development. Here the authors develop a multiplex immunoassay including spike and nucleocapsid proteins of SARS-CoV-2 and the endemic human coronaviruses with high specificity and sensitivity.

Bibliographic Details
Main Authors: Matthias Becker, Monika Strengert, Daniel Junker, Philipp D. Kaiser, Tobias Kerrinnes, Bjoern Traenkle, Heiko Dinter, Julia Häring, Stéphane Ghozzi, Anne Zeck, Frank Weise, Andreas Peter, Sebastian Hörber, Simon Fink, Felix Ruoff, Alex Dulovic, Tamam Bakchoul, Armin Baillot, Stefan Lohse, Markus Cornberg, Thomas Illig, Jens Gottlieb, Sigrun Smola, André Karch, Klaus Berger, Hans-Georg Rammensee, Katja Schenke-Layland, Annika Nelde, Melanie Märklin, Jonas S. Heitmann, Juliane S. Walz, Markus Templin, Thomas O. Joos, Ulrich Rothbauer, Gérard Krause, Nicole Schneiderhan-Marra
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-20973-3

Internet

https://doi.org/10.1038/s41467-021-20973-3

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