Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes

Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes

Summary: Enlargement of the lymphatic vascular network in tumor-draining lymph nodes (LNs) often precedes LN metastasis, likely providing a lymphovascular niche for tumor cells. We investigated morphological and molecular changes associated with the lymphatic remodeling process, using the 4T1 breast...

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Bibliographic Details
Main Authors: Catharina D. Commerford, Lothar C. Dieterich, Yuliang He, Tanja Hell, Javier A. Montoya-Zegarra, Simon F. Noerrelykke, Erica Russo, Martin Röcken, Michael Detmar
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718319132

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http://www.sciencedirect.com/science/article/pii/S2211124718319132

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