Green Analytical Methods of Antimalarial Artemether-Lumefantrine Analysis for Falsification Detection Using a Low-Cost Handled NIR Spectrometer with DD-SIMCA and Drug Quantification by HPLC

Green Analytical Methods of Antimalarial Artemether-Lumefantrine Analysis for Falsification Detection Using a Low-Cost Handled NIR Spectrometer with DD-SIMCA and Drug Quantification by HPLC

Two green analytical approaches have been developed for the analysis of antimalarial fixed dose tablets of artemether and lumefantrine for quality control. The first approach consisted of investigating the qualitative performance of a low-cost handheld near-infrared spectrometer in combination with...

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Bibliographic Details
Main Authors: Moussa Yabré, Ludivine Ferey, Abdoul Karim Sakira, Camille Bonmatin, Clotilde Fauré, Touridomon Issa Somé, Karen Gaudin
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
antimalarial artemether-lumefantrine
green chromatography
accuracy profile
handheld NIR spectrometer
non-destructive analysis
drug falsification detection
Online Access:https://www.mdpi.com/1420-3049/25/15/3397

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https://www.mdpi.com/1420-3049/25/15/3397

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