DNAJB9 suppresses the metastasis of triple-negative breast cancer by promoting FBXO45-mediated degradation of ZEB1

Abstract DNAJB9, a member of the heat shock protein 40 family, acts as a multifunctional player involved in the maintenance of their client proteins and cellular homeostasis. However, the mechanistic action of DNAJB9 in human malignancies is yet to be fully understood. In this study, we found that e...

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Bibliographic Details
Main Authors: Hye-Youn Kim, Young-Mi Kim, Suntaek Hong
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03757-x