Histaminergic transmission slows progression of amyotrophic lateral sclerosis

Histaminergic transmission slows progression of amyotrophic lateral sclerosis

Abstract Background Histamine is an immune modulator, neuroprotective, and remyelinating agent, beneficially acting on skeletal muscles and promoting anti‐inflammatory features in amyotrophic lateral sclerosis (ALS) microglia. Drugs potentiating the endogenous release of histamine are in trial for n...

Full description

Bibliographic Details
Main Authors: Savina Apolloni, Susanna Amadio, Paola Fabbrizio, Giovanna Morello, Antonio Gianmaria Spampinato, Emanuele Claudio Latagliata, Illari Salvatori, Daisy Proietti, Alberto Ferri, Luca Madaro, Stefano Puglisi‐Allegra, Sebastiano Cavallaro, Cinzia Volonté
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
ALS
Histamine
Motor neurons
Microglia
Skeletal muscles
SOD1‐G93A
Online Access:https://doi.org/10.1002/jcsm.12422

Internet

https://doi.org/10.1002/jcsm.12422

Similar Items