Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AITResearch in context

Background: Allergen-specific immunotherapy (AIT) is a causative treatment in allergic airway disease, comprising long-term allergen administration and requiring three years of treatment. Mechanisms and biomarkers that translate into clinical efficacy remain urgently needed. Methods: In an explorato...

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Bibliographic Details
Main Authors: Ulrich M. Zissler, Constanze A. Jakwerth, Ferdinand M. Guerth, Lisa Pechtold, Juan Antonio Aguilar-Pimentel, Katharina Dietz, Kathrin Suttner, Guido Piontek, Bernhard Haller, Zuzana Hajdu, Matthias Schiemann, Carsten B. Schmidt-Weber, Adam M. Chaker
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418303724