Pathological Scenario with the Mannose-Binding Lectin in Patients with IgA Nephropathy

A deeper understanding of the mechanism of complement activation may help to elucidate the pathogenesis of IgA nephropathy (IgAN). Traditionally, the activation of an alternative pathway (AP) has been recognized as an enhancer mechanism of glomerular damage. This paper documents contemporary informa...

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Bibliographic Details
Main Authors: Isao Ohsawa, Masaya Ishii, Hiroyuki Ohi, Yasuhiko Tomino
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/476739