Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation

Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation

Abstract Background Lung cancer is the leading cause of cancer death worldwide. However, the molecular mechanisms underlying lung cancer development have not been fully understood. The functions of histone deacetylases (HDACs), a class of total eighteen proteins (HDAC1–11 and SIRT1–7 in mammals) tha...

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Bibliographic Details
Main Authors: Yubin Lei, Lingling Liu, Shujing Zhang, Shicheng Guo, Xiaoqing Li, Jiucun Wang, Bo Su, Yuchao Fang, Xiaofeng Chen, Hengning Ke, Wufan Tao
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Molecular Cancer
Subjects:
Hdac7
Stat3
Acetylation & phosphorylation
Lung cancer
Online Access:http://link.springer.com/article/10.1186/s12943-017-0736-2

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http://link.springer.com/article/10.1186/s12943-017-0736-2

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