Genome-wide Cas9 binding specificity in Saccharomyces cerevisiae

The CRISPR system has become heavily utilized in biomedical research as a tool for genomic editing as well as for site-specific chromosomal localization of specific proteins. For example, we developed a CRISPR-based methodology for enriching a specific genomic locus of interest for proteomic analysi...

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Bibliographic Details
Main Authors: Zachary J. Waldrip, Piroon Jenjaroenpun, Oktawia DeYoung, Intawat Nookaew, Sean D. Taverna, Kevin D. Raney, Alan J. Tackett
Format: Article
Language:English
Published: PeerJ Inc. 2020-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/9442.pdf