Newcastle disease virus fusion protein is the major contributor to protective immunity of genotype-matched vaccine.

Virulent strains of Newcastle disease virus (NDV) can cause devastating disease in chickens worldwide. Although the current vaccines are substantially effective, they do not completely prevent infection, virus shedding and disease. To produce genotype-matched vaccines, a full-genome reverse genetics...

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Bibliographic Details
Main Authors: Shin-Hee Kim, Nanchaya Wanasen, Anandan Paldurai, Sa Xiao, Peter L Collins, Siba K Samal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3755997?pdf=render