Impaired F<sub>1</sub>F<sub>o</sub>-ATP-Synthase Dimerization Leads to the Induction of Cyclophilin D-Mediated Autophagy-Dependent Cell Death and Accelerated Aging

Mitochondrial F<sub>1</sub>F<sub>o</sub>-ATP-synthase dimers play a critical role in shaping and maintenance of mitochondrial ultrastructure. Previous studies have revealed that ablation of the F<sub>1</sub>F<sub>o</sub>-ATP-synthase assembly factor Pa...

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Bibliographic Details
Main Authors: Verena Warnsmann, Lisa-Marie Marschall, Heinz D. Osiewacz
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/4/757