Differential Effects of Surface-Functionalized Zirconium Oxide Nanoparticles on Alveolar Macrophages, Rat Lung, and a Mouse Allergy Model

Differential Effects of Surface-Functionalized Zirconium Oxide Nanoparticles on Alveolar Macrophages, Rat Lung, and a Mouse Allergy Model

Nanoparticles (NPs) may affect the lung via their chemical composition on the surface. Here, we compared the bioactivity of zirconium oxide (ZrO2) NPs coated with either aminopropilsilane (APTS), tetraoxidecanoic acid (TODS), polyethyleneglycol (PGA), or acrylic acid (Acryl). Supernatants from NPs-t...

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Bibliographic Details
Main Authors: Antje Vennemann, Francesca Alessandrini, Martin Wiemann
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Nanomaterials
Subjects:
macrophage model
intratracheal administration
ZrO2 nanoparticles
inflammation
surface labelling
polyethylene glycol
allergy
Online Access:https://www.mdpi.com/2079-4991/7/9/280

Internet

https://www.mdpi.com/2079-4991/7/9/280

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