Oxidative stress-induced impairment of trophoblast function causes preeclampsia through the unfolded protein response pathway

Oxidative stress-induced impairment of trophoblast function causes preeclampsia through the unfolded protein response pathway

Abstract Pre-eclampsia (PE) is a pregnancy-specific disorder, characterized by hypertension and proteinuria. In PE, trophoblasts mediated inadequate remodeling of uterine spiral arteries seem to interrupt uteroplacental blood flow, one of the hallmarks in the early onset of PE (EO-PE). This, in turn...

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Bibliographic Details
Main Authors: Indrani Mukherjee, Ruby Dhar, Sunil Singh, Jai Bhagwan Sharma, Tapas Chandra Nag, Asit Ranjan Mridha, Parul Jaiswal, Subhrajit Biswas, Subhradip Karmakar
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97799-y

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https://doi.org/10.1038/s41598-021-97799-y

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