High sensitivity of Giardia duodenalis to tetrahydrolipstatin (orlistat) in vitro.

Giardiasis, a gastrointestinal disease caused by Giardia duodenalis, is currently treated mainly with nitroimidazoles, primarily metronidazole (MTZ). Treatment failure rates of up to 20 percent reflect the compelling need for alternative treatment options. Here, we investigated whether orlistat, a d...

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Bibliographic Details
Main Authors: Juliane Hahn, Frank Seeber, Herbert Kolodziej, Ralf Ignatius, Michael Laue, Toni Aebischer, Christian Klotz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23977083/pdf/?tool=EBI