The heterogeneity of lung macrophages in the susceptibility to disease

Alveolar macrophages are specialised resident phagocytes in the alveolus, constituting the first line of immune cellular defence in the lung. As the lung microenvironment is challenged and remodelled by inhaled pathogens and air particles, so is the alveolar macrophage pool altered by signals that m...

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Bibliographic Details
Main Authors: Luisa Morales-Nebreda, Alexander V. Misharin, Harris Perlman, G.R. Scott Budinger
Format: Article
Language:English
Published: European Respiratory Society 2015-09-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/24/137/505.full