Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages

Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages

GPR84 is a member of the metabolic G protein-coupled receptor family, and its expression has been described predominantly in immune cells. GPR84 activation is involved in the inflammatory response, but the mechanisms by which it modulates inflammation have been incompletely described. In this study,...

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Bibliographic Details
Main Authors: Carlota Recio, Daniel Lucy, Gareth S. D. Purvis, Poppy Iveson, Lynda Zeboudj, Asif J. Iqbal, Daniel Lin, Chris O’Callaghan, Lucy Davison, Esther Griesbach, Angela J. Russell, Graham M. Wynne, Lea Dib, Claudia Monaco, David R. Greaves
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
immunometabolism
inflammation
metabolic G protein-coupled receptors
GPR84
macrophages
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01419/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01419/full

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