Effect of starvation on brain glucose metabolism and 18F-2-fluoro-2-deoxyglucose uptake: an experimental in-vivo and ex-vivo study

Effect of starvation on brain glucose metabolism and 18F-2-fluoro-2-deoxyglucose uptake: an experimental in-vivo and ex-vivo study

Abstract Background The close connection between neuronal activity and glucose consumption accounts for the clinical value of 18F-fluoro-2-deoxyglucose (FDG) imaging in neurodegenerative disorders. Nevertheless, brain metabolic response to starvation (STS) might hamper the diagnostic accuracy of FDG...

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Main Authors: Ambra Buschiazzo, Vanessa Cossu, Matteo Bauckneht, Annamaria Orengo, Patrizia Piccioli, Laura Emionite, Giovanna Bianchi, Federica Grillo, Anna Rocchi, Francesco Di Giulio, Francesco Fiz, Lizzia Raffaghello, Flavio Nobili, Silvia Bruno, Giacomo Caviglia, Silvia Ravera, Fabio Benfenati, Michele Piana, Silvia Morbelli, Gianmario Sambuceti, Cecilia Marini
Format: Article
Language:English
Published: SpringerOpen 2018-06-01
Series:EJNMMI Research
Subjects:
Brain metabolism
PET/CT imaging
FDG
Starvation
Neuroimaging
Online Access:http://link.springer.com/article/10.1186/s13550-018-0398-0

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http://link.springer.com/article/10.1186/s13550-018-0398-0

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