The temperature of growth and sporulation modulates the efficiency of spore-display in Bacillus subtilis

Abstract Background Bacterial spores displaying heterologous antigens or enzymes have long been proposed as mucosal vaccines, functionalized probiotics or biocatalysts. Two main strategies have been developed to display heterologous molecules on the surface of Bacillus subtilis spores: (i) a recombi...

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Bibliographic Details
Main Authors: Claudia Petrillo, Stefany Castaldi, Mariamichela Lanzilli, Anella Saggese, Giuliana Donadio, Loredana Baccigalupi, Ezio Ricca, Rachele Isticato
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-020-01446-6