PEP-19 modulates calcium binding to calmodulin by electrostatic steering
The protein PEP-19 increases the rates of calcium binding to calmodulin. Here, the authors report the structure of PEP-19 bound to the C-terminal domain of calmodulin, and are able to propose a mechanism for the observed increased calcium association rate.
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms13583 |