Amyloid β Peptide Specifically Promotes Phosphorylation and Nuclear Translocation of the Extracellular Signal-Regulated Kinase in Cultured Rat Cortical Astrocytes
ABSTRACT: To explore cellular signaling molecules that respond to amyloid β protein (Aβ), we investigated the effect of Aβ on tyrosine phosphorylation of cellular proteins in cultured rat cortical astrocytes. Western blotting with the phosphotyrosine-specific monoclonal antibody 4G10 demonstrated th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2003-01-01
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| Series: | Journal of Pharmacological Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319325769 |