Synthesis and preliminary evaluation of brominated 5-methyl-2,4-dihydropyrazol-3-one and its derivatives as cytotoxic agents

Derivatives of 5-methyl-2,4-dihydro-pyrazol-3-one (1a), 5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one (1b) and 2-(2,4-dinitro-phenyl)-5-methyl-2,4-dihydro-pyrazol-3-one (1c) have been brominated in various ways. The compounds (1a, 1b, 1c) were synthesized by condensation reaction between the ethylacet...

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Bibliographic Details
Main Authors: Rahat Khan, Md. Imam Uddin, Md. Sultan Alam, Mohammad Mamun Hossain, Md. Rabiul Islam
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2008-06-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:http://www.bdjpharmacol.com/0301/27.pdf