Multiscale mathematical modeling in dental tissue engineering: towards computer-aided design of a regenerative system based on hydroxyapatite granules, focusing on early and mid-term stiffness recovery
We here explore for the very first time how an advanced multiscale mathematical modeling approach may support the design of a provenly successful tissue engineering concept for mandibular bone. The latter employs double-porous, potentially cracked, single millimeter-sized granules packed into an ove...
Main Authors: | Stefan Scheiner, Vladimir S. Komlev, Alexey N. Gurin, Christian Hellmich |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-09-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00383/full |
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