Integrin-Mediated Delivery of Drugs and Nucleic Acids for Anti-Angiogenic Cancer Therapy: Current Landscape and Remaining Challenges

Integrin-Mediated Delivery of Drugs and Nucleic Acids for Anti-Angiogenic Cancer Therapy: Current Landscape and Remaining Challenges

Angiogenesis, sprouting of new blood vessels from pre-existing vasculatures, plays a critical role in regulating tumor growth. Binding interactions between integrin, a heterodimeric transmembrane glycoprotein receptor, and its extracellular matrix (ECM) protein ligands govern the angiogenic potentia...

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Bibliographic Details
Main Author: Poulami Majumder
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Bioengineering
Subjects:
Integrin
drug delivery
angiogenesis
anti-angiogenic therapy
siRNA
tumor-homing peptides
combination delivery of drug and nucleic acids
Online Access:http://www.mdpi.com/2306-5354/5/4/76

Internet

http://www.mdpi.com/2306-5354/5/4/76

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