Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes.

Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes.

<h4>Background</h4>Mutations in the Planar Cell Polarity (PCP) core gene Vangl2 cause the most severe neural tube defects (NTD) in mice and humans. Genetic studies show that the Vangl2 gene genetically interacts with a close homologue Vangl1. How precisely Vangl2 and Vangl1 proteins inte...

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Main Authors: Edwige Belotti, Tania M Puvirajesinghe, Stéphane Audebert, Emilie Baudelet, Luc Camoin, Michel Pierres, Lea Lasvaux, Géraldine Ferracci, Mireille Montcouquiol, Jean-Paul Borg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23029439/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23029439/?tool=EBI

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