Pathobiological implications of MUC16 expression in pancreatic cancer.

MUC16 (CA125) belongs to a family of high-molecular weight O-glycosylated proteins known as mucins. While MUC16 is well known as a biomarker in ovarian cancer, its expression pattern in pancreatic cancer (PC), the fourth leading cause of cancer related deaths in the United States, remains unknown. T...

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Main Authors: Dhanya Haridas, Subhankar Chakraborty, Moorthy P Ponnusamy, Imayavaramban Lakshmanan, Satyanarayana Rachagani, Eric Cruz, Sushil Kumar, Srustidhar Das, Subodh M Lele, Judy M Anderson, Uwe A Wittel, Michael A Hollingsworth, Surinder K Batra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3204976?pdf=render