Low-Dose Copper Exposure Exacerbates Depression-Like Behavior in ApoE4 Transgenic Mice

Depression is one of the most common neuropsychiatric disorders. Although the pathogenesis of depression is still unknown, environmental risk factors and genetics are implicated. Copper (Cu), a cofactor of multiple enzymes, is involved in regulating depression-related processes. Depressed patients c...

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Bibliographic Details
Main Authors: Jia Xu, Kaiwu He, Kaiqin Zhang, Chao Yang, Lulin Nie, Ding Dan, Jianjun Liu, Chang-E. Zhang, Xifei Yang
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/6634181