Sequence effect in Parkinson’s disease is related to motor energetic cost

Bradykinesia is the most disabling motor symptom of Parkinson’s disease (PD). The sequence effect, a feature of bradykinesia, refers to the rapid decrement in amplitude and speed of repetitive movements (e.g., gait, handwriting) and is a major cause of morbidity in PD. Previous research has revealed...

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Bibliographic Details
Main Authors: Sule eTinaz, Ajay S Pillai, Mark eHallett
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00083/full