Angiotensin-(1–7) attenuates organ injury and mortality in rats with polymicrobial sepsis

Angiotensin-(1–7) attenuates organ injury and mortality in rats with polymicrobial sepsis

Abstract Background Sepsis and related multiple organ dysfunction result in high morbidity and mortality. Angiotensin (Ang)-(1–7), a biologically active peptide, has various opposing effects of Ang II. Because the effect of Ang-(1–7) on sepsis is unknown, in this study we aimed to determine the impa...

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Bibliographic Details
Main Authors: Hsin-Jung Tsai, Mei-Hui Liao, Chih-Chin Shih, Shuk-Man Ka, Cheng-Ming Tsao, Chin-Chen Wu
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Critical Care
Subjects:
Angiotensin-(1–7)
Apoptosis
Inflammatory response
Organ injury
Polymicrobial sepsis
Online Access:http://link.springer.com/article/10.1186/s13054-018-2210-y

Internet

http://link.springer.com/article/10.1186/s13054-018-2210-y

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