Porcine Circovirus 2 Induction of ROS Is Responsible for Mitophagy in PK-15 Cells via Activation of Drp1 Phosphorylation

Mitochondrial dynamics is essential for the maintenance of cell homeostasis. Previous studies have shown that porcine circovirus 2 (PCV2) infection decreases the mitochondrial membrane potential and causes the elevation of reactive oxygen species (ROS), which may ultimately lead to mitochondrial apo...

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Bibliographic Details
Main Authors: Yikai Zhang, Renjie Sun, Xiaoliang Li, Weihuan Fang
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Viruses
Subjects:
ros
Online Access:https://www.mdpi.com/1999-4915/12/3/289