Experimental Pulmonary Tuberculosis in the Absence of Detectable Brain Infection Induces Neuroinflammation and Behavioural Abnormalities in Male BALB/c Mice

Experimental Pulmonary Tuberculosis in the Absence of Detectable Brain Infection Induces Neuroinflammation and Behavioural Abnormalities in Male BALB/c Mice

Tuberculosis (TB) is a chronic infectious disease in which prolonged, non-resolutive inflammation of the lung may lead to metabolic and neuroendocrine dysfunction. Previous studies have reported that individuals coursing pulmonary TB experience cognitive or behavioural changes; however, the pathogen...

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Bibliographic Details
Main Authors: Jacqueline V. Lara-Espinosa, Ricardo A. Santana-Martínez, Perla D. Maldonado, Mario Zetter, Enrique Becerril-Villanueva, Gilberto Pérez-Sánchez, Lenin Pavón, Dulce Mata-Espinosa, Jorge Barrios-Payán, Manuel O. López-Torres, Brenda Marquina-Castillo, Rogelio Hernández-Pando
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Mycobacterium tuberculosis</i>
neuroinflammation
behaviour abnormalities
Online Access:https://www.mdpi.com/1422-0067/21/24/9483

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https://www.mdpi.com/1422-0067/21/24/9483

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