The features of circulating and tumor-infiltrating γδ T cells in melanoma patients display critical perturbations with prognostic impact on clinical outcome

The features of circulating and tumor-infiltrating γδ T cells in melanoma patients display critical perturbations with prognostic impact on clinical outcome

γδT cells hold a pivotal role in tumor immunosurveillance through their prompt activation and cytokine secretion, their ability to kill tumor cells in an Human Leukocyte Antigen (HLA)-unrestricted manner, and their combination of features of both innate and adaptive immunity. These unique properties...

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Bibliographic Details
Main Authors: Pauline Girard, Julie Charles, Camille Cluzel, Emmanuelle Degeorges, Olivier Manches, Joel Plumas, Florence De Fraipont, Marie-Therese Leccia, Stephane Mouret, Laurence Chaperot, Caroline Aspord
Format: Article
Language:English
Published: Taylor & Francis Group 2019-08-01
Series:OncoImmunology
Subjects:
γδ t cells
melanoma
immune escape
tumor microenvironment
predictive factor
immune checkpoint
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1601483

Internet

http://dx.doi.org/10.1080/2162402X.2019.1601483

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