Protective Effect of CpG-Oligodeoxynucleotides Against Low- and High-LET Irradiation

Protective Effect of CpG-Oligodeoxynucleotides Against Low- and High-LET Irradiation

Background/Aims: CpG-oligodeoxynucleotides (ODNs) are synthetic DNA sequences containing unmethylated cytosine-guanine motifs with potent immunomodulatory effects. Previous reports showed a powerful protective effect of CpG-ODN against the damage induced by low-LET γ-rays. In this study, we...

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Bibliographic Details
Main Authors: Chao Zhang, Min Zheng, Xiang-Hui Zhu, Sha Li, Jin Ni, Bai-Long Li, Hu Liu, Fu Gao, Jian-Ming Cai
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
CpG-ODNs
Irradiation
Carbon beam
High-LET
Online Access:http://www.karger.com/Article/FullText/366368

Internet

http://www.karger.com/Article/FullText/366368

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