The effects of sodium butyrate and inulin supplementation on angiotensin signaling pathway via promotion of Akkermansia muciniphila abundance in type 2 diabetes; A randomized, double-blind, placebo-controlled trial

Introduction: Inflammation has a crucial role in the progression of cardiovascular disease in diabetes. Tumour necrosis factor-α (TNF-α) as an inflammatory marker induces angiotensin II (Ang II) related hypertension pathway in diabetic patients. Gut modulation via prebiotics may ameliorate hypertens...

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Main Authors: Neda Roshanravan, Reza Mahdavi, Effat Alizadeh, Abed Ghavami, Yalda Rahbar Saadat, Naimeh Mesri Alamdari, Shahriar Alipour, Mohammad Reza Dastouri, Alireza Ostadrahimi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2017-12-01
Series:Journal of Cardiovascular and Thoracic Research
Subjects:
Online Access:https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-9-183.pdf