5-HT3 receptor antagonists protect against pressure overload-induced cardiac hypertrophy in murine

Activation of cardiac sympathetic afferent reflex results in the increase of sympathetic activity. Serotonin (5-HT) activates cardiac sympathetic afferent through stimulating 5-HT3 receptors, the aim of present study is to test whether 5-HT3 receptor antagonists protect against cardiac hypertrophy....

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Bibliographic Details
Main Authors: Rong Huo, Chang Chen, Yan Chen, Zhe Li, Yunlong Hou, Deli Dong
Format: Article
Language:English
Published: Elsevier 2012-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383511001122