Farrerol Induces Cancer Cell Death via ERK Activation in SKOV3 Cells and Attenuates TNF-α-Mediated Lipolysis

Farrerol Induces Cancer Cell Death via ERK Activation in SKOV3 Cells and Attenuates TNF-α-Mediated Lipolysis

Farrerol (FA) is a flavanone isolated from the Chinese herbal medicine “Man-shan-hong” (<i>Rhododendron dauricum</i> L.). In the present study, FA decreased the viability of SKOV3 cells in a dose- and time-dependent manner, and it induced G2/M cell cycle arrest and cell apoptosis. Cell c...

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Bibliographic Details
Main Authors: Jongbeom Chae, Jin Soo Kim, seok tae Choi, Seul Gi Lee, Oyindamola Vivian Ojulari, Young Jin Kang, Taeg Kyu Kwon, Ju-Ock Nam
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
antitumor effect
adipogenesis
cachexia
cell cycle arrest
farrerol
ovarian cancer
Online Access:https://www.mdpi.com/1422-0067/22/17/9400

Internet

https://www.mdpi.com/1422-0067/22/17/9400

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