Immunohistochemical investigation of cell cycle and apoptosis regulators (Survivin, β-Catenin, P53, Caspase 3) in canine appendicular osteosarcoma

<p>Abstract</p> <p>Background</p> <p>Osteosarcoma (OSA) represents the most common canine primary bone tumour. Despite several pathways have been investigated so far, few molecules have been identified as prognostic tools or potential therapeutic targets, and there is s...

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Bibliographic Details
Main Authors: Bongiovanni Laura, Mazzocchetti Francesca, Malatesta Daniela, Romanucci Mariarita, Ciccarelli Andrea, Buracco Paolo, De Maria Raffaella, Palmieri Chiara, Martano Marina, Morello Emanuela, Maniscalco Lorella, Salda Leonardo
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Veterinary Research
Online Access:http://www.biomedcentral.com/1746-6148/8/78