Mitochondrial inverted repeats strongly correlate with lifespan: mtDNA inversions and aging.

Mitochondrial defects are implicated in aging and in a multitude of age-related diseases, such as cancer, heart failure, Parkinson's disease, and Huntington's disease. However, it is still unclear how mitochondrial defects arise under normal physiological conditions. Mitochondrial DNA (mtD...

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Bibliographic Details
Main Authors: Jiang-Nan Yang, Andrei Seluanov, Vera Gorbunova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3775743?pdf=render