Electroconvulsive seizures influence dendritic spine morphology and BDNF expression in a neuroendocrine model of depression

Background: Electroconvulsive therapy (ECT) is a rapid and effective treatment for major depressive disorder. Chronic stress-induced depression causes dendrite atrophy and deficiencies in brain-derived neurotrophic factor (BDNF), which are reversed by anti-depressant drugs. Electroconvulsive seizure...

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Bibliographic Details
Main Authors: Kristen. R. Maynard, John W. Hobbs, Sumita K. Rajpurohit, Keri Martinowich
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Brain Stimulation
Subjects:
ECT
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X18301049