Archaeal Tuc1/Ncs6 homolog required for wobble uridine tRNA thiolation is associated with ubiquitin-proteasome, translation, and RNA processing system homologs.

Archaeal Tuc1/Ncs6 homolog required for wobble uridine tRNA thiolation is associated with ubiquitin-proteasome, translation, and RNA processing system homologs.

While cytoplasmic tRNA 2-thiolation protein 1 (Tuc1/Ncs6) and ubiquitin-related modifier-1 (Urm1) are important in the 2-thiolation of 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) at wobble uridines of tRNAs in eukaryotes, the biocatalytic roles and properties of Ncs6/Tuc1 and its homologs are po...

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Main Authors: Nikita E Chavarria, Sungmin Hwang, Shiyun Cao, Xian Fu, Mary Holman, Dina Elbanna, Suzanne Rodriguez, Deanna Arrington, Markus Englert, Sivakumar Uthandi, Dieter Söll, Julie A Maupin-Furlow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4048286?pdf=render

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http://europepmc.org/articles/PMC4048286?pdf=render

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