The Triform algorithm: improved sensitivity and specificity in ChIP-Seq peak finding

<p>Abstract</p> <p>Background</p> <p>Chromatin immunoprecipitation combined with high-throughput sequencing (ChIP-Seq) is the most frequently used method to identify the binding sites of transcription factors. Active binding sites can be seen as peaks in enrichment prof...

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Bibliographic Details
Main Authors: Kornacker Karl, Rye Morten, Håndstad Tony, Drabløs Finn
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2105/13/176